Photodynamic therapy (PDT) is a special form of phototherapy, a term which includes all treatments which use light to induce reactions in the body which are of benefit to patients.

PDT is a developing technique which can potentially destroy unwanted tissue, whilst sparing normal tissue. First a drug called a photosensitizer is administered to the patient usually by injection (Dr. Lashgari uses a topical). The photosensitizer alone is harmless and has no effect on either healthy or abnormal tissue. However, when light (often from a laser) is directed onto tissue containing the drug, the drug becomes activated and the tissue is rapidly destroyed, but only precisely where the light has been directed. Thus, by careful application of the light beam, the technique can be targeted selectively to the abnormal tissue.

Some of the drugs being developed also have the desirable property of concentrating in tumors (and certain other kinds of proliferating tissue) relative to the surrounding healthy tissue, which also helps in targeting. There is only one potentially adverse effect – some drugs can result in skin photosensitivity, which means that patients must stay out of bright light for some time following the administration of the drug.

Dr. Lashgari uses a combination of a photosensitizer, called amino-levulinic acid (ALA) and a light source called IPL.  ALA is in the form of a solution which is applied to the skin for 1 hour prior to the application of the light, IPL. The cream is concentrated in certain sundamaged tissue, such as actinic keratoses (pre-cancers) because these lesions are more rapidly proliferating.  Then the application of the light beam causes the activation of the drug, which helps destroy these pre-cancers.  The IPL also interacts with aging spots, and excess blood vessels helping improve the complexion.  Finally, repeat treatments can help improve the texture of the skin, fine lines, and pores. (see photofacials).

There may be redness and peeling after the treatment for up to a week.  The patients will be sensitive to sunlight for 24-48 hrs after the treatment.  Strict sun protection (with zinc or titanium oxide) with a broad spectrum SPF 30 sunblock is required. 

Dr. Lashgari or staff will advise on the appropriate moisturizers and topical creams to be used during and after the recovery period.
Please call us and set up a consultation with Dr. Lashgari to determine whether you're a candidate for this exciting new treatment for sundamage and pre-cancers.